Bigg Boss Fame Sana Makbul Reveals Liver Cirrhosis Diagnosis, Know All About It

Bigg Boss Fame Sana Makbul Reveals Liver Cirrhosis Diagnosis, Know All About It

Last Updated:June 16, 2025, 09:58 IST

In a recent interview, Sana Makbul revealed that her autoimmune hepatitis has worsened to liver cirrhosis. Here’s all that you need to know about this condition.

Sana mentioned how she is trying to avoid a liver transplant and is focusing on immunotherapy.

Actor and winner of Bigg Boss OTT 3, Sana Makbul, recently revealed that she has been diagnosed with liver cirrhosis. The news left her fans shocked, and many took to social media to send her strength and prayers for her well-being. The actor was admitted to the hospital earlier this month when the situation worsened.

In a conversation with Hindustan Times, Sana Makbul talked about being diagnosed with liver cirrhosis. The actor said, “I’ve been living with autoimmune hepatitis for a while now, but recently things got worse. My immune system started attacking my liver more aggressively, and I’ve now been diagnosed with liver cirrhosis. But I’m trying to stay strong and taking one day at a time.” Sana mentioned how she is trying to avoid a transplant and is focusing more on immunotherapy and recovery.

What is Autoimmune Hepatitis and Liver Cirrhosis?

Autoimmune hepatitis is a chronic liver condition in which the body’s immune system mistakenly attacks healthy liver cells, triggering inflammation. If left untreated, this ongoing inflammation can lead to serious complications such as liver fibrosis or cirrhosis, just like in Sana’s case.

Cirrhosis represents the advanced stage of liver damage, where healthy tissue is gradually replaced by scar tissue. This scarring occurs as the liver attempts to repair itself, but ultimately hampers its ability to function properly. According to medical experts, cirrhosis is a progressive disease – initially, the body may compensate for reduced liver activity, often masking symptoms. However, as more scar tissue builds up, liver function deteriorates significantly, eventually leading to noticeable and potentially life-threatening symptoms.

What Are the Symptoms?

Autoimmune hepatitis often develops gradually, and symptoms may vary in intensity. While some people may remain asymptomatic for years, others experience noticeable signs. Common symptoms include:

  • Fatigue and weakness
  • Abdominal discomfort, particularly in the upper right side
  • Jaundice (yellowing of the skin and eyes)
  • Dark urine and pale stools
  • Joint pain
  • Loss of appetite and weight loss
  • Nausea or vomiting
  • Skin rashes or spider-like blood vessels on the skin
  • In women, irregular menstrual cycles

Who Is at Risk of Autoimmune Hepatitis?

Autoimmune hepatitis can affect individuals of any age or background, but certain groups are more susceptible. Women, particularly between the ages of 15 and 40, are significantly more likely to develop the condition. A family history of autoimmune disorders can elevate the risk, as can the presence of other autoimmune diseases such as type 1 diabetes, rheumatoid arthritis, celiac disease, or autoimmune thyroiditis.

How Is It Diagnosed and What Are the Treatment Options?

Diagnosis: Autoimmune hepatitis is diagnosed using a combination of blood tests, imaging, and liver biopsy.

Treatment Options: The main aim of treatment is to calm the immune system, reduce inflammation in the liver, and stop the disease from progressing to cirrhosis. Doctors usually start with corticosteroids to control the immune response. Sometimes, other medicines called immunosuppressants are added to help reduce side effects and keep the disease under control. In very severe cases, where the liver is badly damaged and not responding to treatment, a liver transplant may be needed. In case of cirrhosis, like Sana, doctors recommend immunotherapy, regular monitoring, and a liver transplant in extreme cases.

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