Last Updated:July 02, 2025, 11:03 IST
Shefali Jariwala’s death sparks concern; cardiologist explains Glutathione risks
Shefali Jariwala died on June 27 (Credits: Instagram)
The sudden death of actress and model Shefali Jariwala has left fans shocked and grieving — and raised troubling questions about the possible misuse of glutathione injections, often marketed as a quick fix for skin lightening and detoxification. While the exact cause of death remains unconfirmed, growing concern over the unregulated use of glutathione in the beauty and wellness industry has prompted medical experts to weigh in.
Dr. Sanjeeva Kumar Gupta, Consultant, Department of Cardiology, CK Birla Hospital, Delhi, stresses that while glutathione is a powerful antioxidant naturally produced in the body, its supplementation — especially via intravenous (IV) methods — must be approached with extreme caution.
“Among the available modes, oral and sublingual supplements are the safest and most convenient for regular use,” says Dr. Gupta. “Liposomal formulations now offer improved absorption despite glutathione’s traditionally low oral bioavailability.”
By contrast, IV glutathione — frequently promoted in clinics for cosmetic benefits — delivers the compound directly into the bloodstream and offers high bioavailability, but comes with risks. “It should only be administered under strict medical supervision,” he warns. “Adverse effects can include allergic reactions, inflammation of the veins, or even a sudden drop in blood pressure.”
As for dosage, Dr. Gupta explains it should be tailored to individual health goals. For general wellness, 250–500 mg per day orally is common, while higher doses for skin concerns should only be taken under a doctor’s guidance. IV doses can range from 600 mg to 2,400 mg per session — again, strictly in clinical settings.
He also advises caution for individuals with underlying medical conditions, pregnant or breastfeeding women, and those on medications. “Always consult a qualified healthcare provider before starting glutathione,” Dr. Gupta says.
In the wake of Shefali’s tragic passing, experts are urging a return to medically sound decisions over aesthetic shortcuts. The message is clear: beauty should never come at the cost of safety.

Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she’s a weaver of wit and wisdom in the digital landscape. As a key figure in News18 Engl…Read More
Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she’s a weaver of wit and wisdom in the digital landscape. As a key figure in News18 Engl… Read More
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